EPOR Protein (C-Term, Extracellular Domain)

N° du produit ABIN1684690

Cette protéine Recombinant EPOR est produite dans HEK-293T Cells.

Aperçu rapide pour EPOR Protein (C-Term, Extracellular Domain) (ABIN1684690)

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293T Cells

Pureté: > 97 %, as determined by SDS-PAGE and HPLC

Détail du produit

Attributs du protein: C-Term, Extracellular Domain

Specificité: Optimized DNA sequence encoding extracellular domain of mouse erythropoietin receptor including a C-terminal His tag was expressed in HEK293 cells.

Attributs du produit: Recombinant mouse EPO receptor is a monomer protein consisting of37 amino acid residue subunits, due to glycosylation migrates as an approximately 35 kDa protein on SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Information d'application

Restrictions: For Research Use only

Stockage

Buffer: PBS solution, pH7.2

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

Date de péremption: 12-24 months

Détail du antigène

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Autre désignation: EPOR

Sujet: Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils monocytes and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal cascade within the cell. Expression of MCP-4/CCL13 mRNA and protein is greater in the sputum, epithelium, submucosal inflammatory cells and bronchoalveolar lavage fluid of asthmatics than in healthy individuals. Involvement of MCPs has also been demonstrated in renal inflammation and atopic dermatitis and the expression of this protein is also correlated with enhanced inflammatory immune responses during immunotherapy

UniProt: P14753

Pathways: Signalistation JAK/STAT